The atmospheric science of JEM-EUSO

An Atmospheric Monitoring System (AMS) is critical suite of instruments for JEM-EUSO whose aim is to detect Ultra-High Energy Cosmic Rays (UHECR) and (EHECR) from Space. The AMS comprises an advanced space qualified infrared camera and a LIDAR with cross checks provided by a ground-based and airborne Global Light System Stations. Moreover the Slow Data Mode of JEM-EUSO has been proven crucial for the UV background analysis by comparing the UV and IR images. It will also contribute to the investigation of atmospheric effects seen in the data from the GLS or even to our understanding of Space Weather

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Sugar cane dry yeast in feeding for growing and finishing goat kids Levedura seca de cana-de-açúcar na alimentação de cabritos em crescimento e terminação

It was used 27 goat kids (18 ¾ Boer + ¼ Saanen and nine Saanen; 18.0 ± 1.60 kg) distributed in a completely randomized design with factorial arrangement to evaluate productive performance and the total digestibility of dry matter and nutrients in the rations. Diets were composed of soybean meal, soybean meal + dry yeast or dry yeast as protein source, oat hay, ground corn and vitamin-mineral mixture with mean composition of 2.50 Mcal of ME/kg DM and 17.0% of crude protein on average. Digestibility was determined using indigestible neutral detergent fiber as marker. Intakes of dry matter, organic matter, crude protein and total carbohydrates were not altered by rations. However, inclusion of dry yeast in the rations reduced ingestions of ether extract, neutral detergent fiber and acid detergent fiber. Within breed groups, the ¾ Boer + ¼ Saanen goat kids showed the highest intakes of dry matter and nutrients, as well as the best means of daily gain, feed conversion and days in feedlot. Digestibilities of dry matter, organic matter, crude protein and total carbohydrates were higer - and the digesbility of ether extract was lower - for animals fed rations with dry yeast. There were no differences in digestibility of neutral detergent fiber. Rations with dry yeast showed the highest values of total digestible nutrients. Dry yeast can be used as alternative protein source in rations for goat kids because it does not change animal performance and it does have higher nutritional value than soybean meal. ¾ Boer + ¼ Saanen kids show, in feedlots, better performance in growth and finishing phases when compared to Saanen kids.<br>Foram utilizados 27 cabritos (18 ¾ Boer + ¼ Saanen e 9 Saanen; 18,0 ± 1,60 kg) distribuídos em delineamento inteiramente casualizado com arranjo fatorial para avaliar o desempenho produtivo e a digestibilidade total da matéria seca e dos nutrientes das rações. As dietas foram compostas de farelo de soja, farelo de soja + levedura seca ou levedura seca como fonte de proteína, feno de aveia, milho moído e mistura vitamínico-mineral, com composição média de 2,50 Mcal de EM/kg de matéria seca e 17,0% de proteína bruta. A digestibilidade foi determinada utilizando-se fibra em detergente neutro indigestível como indicador. As ingestões de matéria seca, matéria orgânica, proteína bruta e carboidratos totais não foram influenciadas pelas rações. No entanto, a inclusão de levedura seca nas rações reduziu as ingestões de extrato etéreo, fibra em detergente neutro e fibra em detergente ácido. Dentro dos grupos raciais, os cabritos ¾ Boer + ¼ Saanen foram os que apresentaram maior ingestão de matéria seca e nutrientes, assim como melhores médias de ganho diário, conversão alimentar e dias em confinamento. A digestibilidade de matéria seca, matéria orgânica, proteína bruta e carboidratos totais foi maior - e a de extrato etéreo menor - nos animais alimentados com as rações contendo levedura seca. Não houve diferenças na digestibilidade de fibra em detergente neutro. As rações com levedura seca apresentaram maiores valores de nutrientes digestíveis totais. A levedura seca pode ser usada como fonte proteica alternativa em rações para cabritos, pois não altera o desempenho dos animais e tem valor nutritivo superior ao do farelo de soja. Cabritos ¾ Boer + ¼ Saanen apresentam, em confinamento, melhor desempenho produtivo nas fases de crescimento e terminação em comparação aos cabritos Saanen